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Do not use zyban if you have used an mao inhibitor in the past 14 days.

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Report any new or worsening symptoms to your doctorsuch asmood or behavior changesanxietydepressionpanic attackstrouble sleepingor if you feel impulsiveirritableagitatedhostileaggressiverestlesshyperactivementally or physicallyor have thoughts about suicide or hurting yourself.

Concomitant use of Zyban and monoamine oxidase inhibitorsMAOIsis contraindicatedAt least 14 days should elapse between discontinuation of irreversible MAOIs and initiation of treatment with ZybanFor reversible MAOIsa 24 hour period is sufficient.

Take the missed dose as soon as you rememberSkip the missed dose if it is almost time for your next scheduled doseDo not take extra medicine to make up the missed dose.

Nicotineadministered transdermally by patchesdid not affect the pharmacokinetics of bupropion and its metabolites.

Zyban is contraindicated in patients with a current seizure disorder or any history of seizures.

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zyban is contraindicated in patients with a current or previous diagnosis of bulimia or anorexia nervosa.

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